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Guy Bradley, Ph.D.
Soichi Haraguchi, Ph.D.
A graduate from Eckerd College (BS with Honors in Biology) and the University of South Florida College of Medicine’s Department of Medical Microbiology and Immunology (Ph.D. with Honors in Medical Sciences), Dr. Bradley has been published in numerous scientific journals and books and has been awarded several national and international patents based on his discoveries.
Dr. Bradley received the Sigma Xi Research Award in 1990, the first Baxter Diagnostics Microscan Young Investigator’s Award in 1992 for his outstanding contributions to medical microbiology, and in 2002, Eckerd College’s Robert A. Staub Distinguished Teacher award.
He was the Director of the Laboratory of Immunosuppressive Retrovirology at All Children’s Hospital, St. Petersburg, FL (1991-1994) where his lab focused on understanding the ability of HIV to be transmitted from mother to fetus and the development of drug resistant virus in HIV+ children. While at All Children’s Hospital he also co-authored papers describing the effects of chronic calorie restriction on the immune response and on the identification of the stem cell capable of repopulating the entire hematopoietic system.
From 1992-2003, Dr. Bradley served as a clinical assistant professor in the Department of Medical Microbiology and Immunology at the University of South Florida College of Medicine. As such he served as the research advisor for several graduate students pursuing their degrees.
From 1994 to Sept 2000, Dr. Bradley was an Assistant Professor of Molecular Physiology at Eckerd College and was then promoted to Associate Professor in 2000.
From 1999 to 2003, Dr. Bradley served as an Assistant Member at the Tampa Bay Research Institute. In 2003, he was promoted to Associate Member and Principal Investigator and then in 2018 he was promoted to Senior Member at the Institute.
Dr. Bradley has been associated with the Tampa Bay Research Institute since 1982, first as an undergraduate, then as a graduate student, and now as one of the Institute’s Senior Members and principal investigators. His laboratory is currently investigating the mechanisms by which a pine cone extract is able to modulate the immune response to cancer, vaccines, allergens, and to slow the progress of Alzheimer's disease. The goal of his laboratory is to isolate the active molecules within the extract in order to better understand how they can be utilized to boost the effectiveness of drugs and vaccines used in the treatment of cancer and chronic debilitating diseases.
Dr. Haraguchi received his Ph.D. in Medical Sciences (Microbiology and Immunology) from the Hamamatsu University School of Medicine, Hamamatsu, Japan, and M.S. as well as B.S in Pharmacy from the Soichi Haraguchi, Ph.D. a molecular biologist / immunologist has recently joined TBRI as a Principal Investigator. Dr. Haraguchi has extensive experience in basic and clinical immunology. His expertise covers a variety of cellular, molecular, and biochemical studies on microbial infections, hormones, cancers, and immunodeficiencies
He is originally from Hamamatsu, Japan, and has resided in the United States since 1989. Soichi was a faculty member at the Hamamatsu University School of Medicine and emigrated to the U.S. in 1989 to accept a postdoctoral fellowship position in the Department of Pediatrics at the University of South Florida.
From 1994 to 2006, Dr. Haraguchi led the Retrovirology Laboratory at All Children’s Hospital. He developed methods examining immunological processes and deficiencies for the immunosuppressed HIV patients and patients with genetically-inherited immunodeficiencies at a molecular level.
Dr. Haraguchi has been invited to present his work at several scientific meetings and has received several research grants from the American Cancer Society and the Eleanor Naylor Dana Foundation. He was also appointed as a member of the H. Lee Moffitt Cancer & Research Institute and Institute for Biomolecular Science at USF, and elected to membership of the prestigious American Association of Immunologists and American Association for Cancer Research.
PRINCIPAL INVESTIGATORS
Akiko Tanaka, Ph.D. (President and Senior Member)
Dr. Tanaka co-founded Tampa Bay Research Institute (TBRI, formerly known as Showa University Research Institute) in 1981 as the first independent biomedical research institute in the State of Florida, where she has been dedicated to solving the puzzle of life-threatening diseases. She became TBRI’s President in 1995.
Her research in biomedicine is helping to popularize the concept of Complementary/Integrative Medicine (CIM), in which Western biomedical science is afforded the insights provided by the age-old practice of Eastern folk medicine. CIM is a holistic approach to the development of safer and more effective medical interventions and will help to facilitate the wider adoption of personalized medicine. The knowledge gained through her long-term research efforts has contributed to our understanding of the cause, cure and prevention of several chronic diseases.
Dr. Tanaka’s work on the biological properties of a folk remedy— specifically an extract from the pinecone, termed a polyphenylpropenoid-polysaccharide complex (PPC)—has resulted in the award of 14 U.S. and foreign patents to date. As a result, PPC was developed into ImmunExtra, a commercially available dietary supplement.
Dr. Tanaka earned her Ph.D. in Medical Science/Microbiology (Igaku Hakase) and a B.S. degree in Pharmaceutical Science, both from Showa University in Tokyo, Japan. Her postgraduate and professional experience included research projects with Life Sciences Research Laboratories in St. Petersburg, Rush-Presbyterian-St. Luke's Medical Center and the Department of Microbiology at the University of Illinois in Chicago, the Department of Bacteriology at the University of North Carolina at Chapel Hill, and The Institute for Virus Research at Kyoto University in Japan. In 2005 she was awarded an honorary Doctor of Science degree from Eckerd College in St. Petersburg.
Throughout the 1980s and 1990s, Dr. Tanaka served as a clinical Associate Professor in the Department of Pharmacology at the University of South Florida in Tampa and as a visiting Associate Professor at Showa University in Japan. She now serves as a visiting Professor at Niigata University of Pharmacy and Applied Life Sciences in Japan.
She and her team at TBRI have hosted eight national and international conferences relating to chronic diseases. Dr. Tanaka has been awarded research grants, including those from the U.S. National Institutes of Health, the U.S. Department of Agriculture, the American Cancer Society and the American Heart Association.
Dr. Tanaka has overcome many obstacles as a female scientist embarking on a career in biomedical research, and she has used that experience to mentor future female scientists. She has received several awards in recognition of her work on behalf of women’s advocacy. She was named the Business Woman of the Year by the St. Petersburg Chamber of Commerce in 2002 and was inducted into the St. Petersburg Chamber of Commerce’s Women’s Hall of Fame in 2003. She won the inaugural Outstanding Woman in Science Award at the 50th Anniversary celebration of Girls, Inc. of Pinellas in 2012.
